Recombinant Filaggrin anticorps (AA 198-288)

N° du produit ABIN7126404

L’anticorps Lapin Monoclonal anti-Filaggrin a été validé pour WB. Il convient pour détecter Filaggrin dans des échantillons de Humain.

Aperçu rapide pour Recombinant Filaggrin anticorps (AA 198-288) (ABIN7126404)

Antigène: Filaggrin (FLG)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Filaggrin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Filaggrin anticorps

Épitope: AA 198-288

Specificité: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules.Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human Filaggrin protein fragment (around aa 198-288) (exact sequence is proprietary)

Isotype: IgG

Information d'application

Indications d'application:

Known_Application: Western Blot (2-4 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: U-251-MGor A-431 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Filaggrin

Antigène: Filaggrin (FLG)

Autre désignation: FLG

Sujet: ATOD2, Epidermal Filaggrin, Filaggrin, Filaggrin precursor, Fillagrin, FLG, Profilaggrin,Filaggrin (Keratinocyte Differentiation Marker)
Cellular localisation: Cytoplasm

Poids moléculaire: 26-45kDa (Processed), 350kDa (Profilaggrin)

ID gène: 2312, 654510

UniProt: P20930

Pathways: Sensory Perception of Sound, Stem Cell Maintenance